In its commitment to transparency and efficiency, Grifols prepared its Integrated and Sustainability Annual Report following the recommendations contained in “International Integrated Reporting Framework” of the International Integrated Reporting Council (IIRC) and the “Guidelines for Preparation of the Listed Company Management Reports” of the Spanish National Securities Market Commission.

This report, subject to independent review, presents group’s financial and non-financial information in compliance with current regulatory provisions¹.

This Integrated and Sustainability Annual Report is an exact copy of the Consolidated Non-Financial Information Statement. This report complies with the disclosure requirements for a Statement of Non-Financial Information (see Annex VI “Index of context required by Law 11/2018, of December 28, regarding non-financial information and diversity”), which offers an overview of the impact of Grifols’ activity on the employee pool, environmental and social issues, human rights, and the fight against corruption and bribery, including measures to promote the principles of equality and opportunity among men and women, non-discrimination, inclusion of people with disabilities and universal accessibility.

This report has been prepared in accordance with GRI standards as detailed in Annex VII “GRI Content Index.” Also included are SASB standards relating to the “Biotechnology and Pharmaceuticals” sector, as per Annex VIII “SASB Content Index.”

Grifols’ efforts to promote the Sustainable Development Goals are outlined in Annex IX “Index of Grifols’ contribution to the SDGs and the principles of the United Nations Global Compact,” including information on priority SDGs and main contributions in 2023. In line with its formal adherence to the United Nations Global Compact, Grifols complies with the Communication on Progress (CoP) with this report.

This report describes the actions the company has taken and plans to take to implement the Global Compact Principles in the areas of human rights, labor, environment and anti-corruption, and their measurable outcomes. All measurable results are well described in each of the chapters of this report.

Unless stated to the contrary, the financial information presented in this report coincides with the Consolidated Financial Statements for the year ended December 31, 2023. It should be read jointly with the 2023 Consolidated Financial Statements, which have been subject to an external audit. Some financial indicators and ratios are classified as Alternative Performance Metrics (APMs) in accordance with European Securities Markets Authority (ESMA) guidelines.

1. Among others, the Commercial Code, Consolidated Text of the Capital Companies Act and Law 11/2018, of December 28, which amends the Commercial Code, Consolidated Text of the Capital Companies Act and Accounts Auditing Act with regard to non-financial information and diversity, and which transposes Directive 2014/95/EU into Spanish law with regard to the disclosure of non- financial information.

In accordance with Law 11/2018 of December 28 on non-financial information and diversity, the Board of Directors of Grifols, S.A. (Grifols hereinafter) prepares the Non-Financial Information Statement for the fiscal year 2023 as a separate document and an integral part of the Consolidated Directors’ Report and as a separate document from the consolidated annual accounts. This report is publicly available on Grifols’ corporate website at www.grifols.com. This Integrated and Sustainability Annual Report is an exact copy of the Consolidated Non-Financial Information Statement.

Grifols analyzed the materiality of the requirements by Law 11/2018 while considering the opinion of its main stakeholders. As shown in Annex VI, “Index of the contents required by Law 11/2018, of December 28,” the Non-Financial Information Statement was prepared in accordance with the Global Reporting Initiative (GRI) Standards selected for requirements considered material to the business.